neurofibrillary tangles การใช้

• This amyloid protein forms plaques and neurofibrillary tangles that progress through the brain.
• Both amyloid plaques and neurofibrillary tangles are clearly visible by microscopy in AD brains.
• The brain regions affected contain neurofibrillary tangles, similar to those seen in Alzheimer's disease.
• Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer's disease.
• Alzheimer's disease causes inflammation in the neurons by its deposits of amyloid beta peptides and neurofibrillary tangles.
• Examples include Mallory body, Fatty liver, Howell-Jolly body, Neurofibrillary tangle, etc . There are also many of these in the general.
• Senile plaques and neurofibrillary tangles are present in nearly all by 35 years of age, though dementia may not be present.
• Alzheimer s Disease ( AD ) is a neurodegenerative condition characterized by two hallmarks : senile plaques and the neurofibrillary tangle.
• Neurofibrillary tangles and senile plaques, characteristic of Alzheimer's disease ( AD ), are not common unless the person is demented . ""
• The cholinergic hypothesis of geriatric memory dysfunction is an older hypothesis that was considered before beta-amyloid deposits, neurofibrillary tangles, or neuritic plaques.
• There are many activated microglia over-expressing IL-1 in the brains of Alzheimer patients that are distributed with both A? plaques and neurofibrillary tangles.
• Neurofibrillary tangles, one of the hallmarks of the Alzheimer's-afflicted brain, are bundles of abnormal filaments made up of a brain protein called " tau ."
• Research has also indicated that patients with AD and comorbid depression show higher levels of neurofibrillary tangle formation than individuals with AD but no depression.
• This gene encodes a protein associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease.
• The difference in memory between normal aging and a memory disorder is the amount of beta-amyloid deposits, hippocampal neurofibrillary tangles, or neuritic plaques in the cortex.
• Post-morten studies reveal that Alzheimer's brains are usually shrunken and riddled with the amyloid plaques and formations called neurofibrillary tangles _ twisted pairs of nerve fibers.
• Neurofibrillary tangles were first described by Alois Alzheimer in one of his patients suffering from Alzheimer's disease ( AD ), which is considered a secondary tauopathy.
• Neurofibrillary tangle and modified Braak scores were lower in AD + DLB, however, neocortical NFT scores show markedly different patterns between AD + DLB and Classical Alzheimers.
• The most typical symptom of Alzheimer's disease, dementia, occurs in advanced stages of PD, while it is common to find neurofibrillary tangles in brains affected by PD.
• In a genome wide association screen ( GWAS ), CASS4 showed a significant correlation with clinical pathological features of AD such as neurofibrillary tangles and neuritic plaques.